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John S. Greenspan, BDS, PhD

Dr. Greenspan and his group have for over 25 years been leaders in studies of oral aspects of HIV infection. He and his colleagues, notably Dr. Deborah Greenspan, have made major contributions to HIV research and care including the discovery of the lesion hairy leukoplakia, its association with EBV, and the significance of this and other oral lesions in the natural history of HIV disease.

He is professor of oral pathology and serves as the associate dean for global oral health of the School of Dentistry at the University of California, San Francisco (UCSF). Dr. Greenspan is a professor of pathology in the School of Medicine and is former chair of both the UCSF Academic Senate and the UC systemwide Health Sciences Committee. He is founding director of three pioneering components of UCSF's world-renowned AIDS program: the Oral AIDS Center, the campuswide California AIDS Research Center, and the UCSF AIDS Specimen Bank; and headed the campus's $140 million-per-year AIDS research efforts as director of the AIDS Research Institute at UCSF from 2003 to 2012. Dr. Greenspan is also director of the Sjögren's International Collaborative Clinical Alliance, the world's largest ongoing longitudinal cohort study of that autoimmune disease.

He is a fellow of the UK Royal College of Pathologists; of King's College, London; and of the American Association for the Advancement of Science. He was chair of the UCSF Department of Stomatology from 1988 until 2001. That department included the divisions of oral biology; oral medicine, pathology and radiology; and periodontology. He was chairman of the dentistry section of the American Association for the Advancement of Science in 1992-1993, president of the American Association for Dental Research in 1988-1989, president of the International Association for Dental Research (IADR) in 1996-1997, president of the IADR Experimental Pathology Group in 1983-1984, and member of the Council on Dental Research of the American Dental Association 1987–1990. In 1995, Dr. Greenspan was elected to membership in the Institute of Medicine of the US National Academy of Sciences. He was the Kreshover lecturer at the NIH in 1989 and was awarded the honorary degree of ScD by Georgetown University in 1990 and the fellowship in Dental Surgery of the Royal College of Surgeons of England in 1998.

Dr. Greenspan's research interests include the oral aspects of AIDS and the role of viruses in oral epithelial and salivary gland lesions. He has published close to 300 papers and four books on oral aspects of AIDS, oral pathology, and immunopathology. He has been a featured speaker at many international meetings and has presented over 250 research papers, clinics, and postgraduate courses. He has trained over 40 basic and clinical science graduate students and over 20 fellows, including a number of now-prominent dentist-scientists and physician-scientists. He has also acted as mentor to many other academic clinician-scientists at formative stages of their careers. He was previously lecturer, then senior lecturer and honorary consultant in Oral Pathology at the Royal Dental School, London, 1963–1976; and honorary consultant at St. George's Hospital in London.

 

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